The Plaza de la Independencia is an emblematic public space located in the Old Town of Panama. Also known as Plaza Mayor, this historic plaza is a site of great importance in the history of Panama and has witnessed numerous important events over the years. The Plaza de la Independencia is surrounded by imposing colonial buildings, and in its center stands a monument dedicated to the heroes of Panama's independence from Spain in 1821. This monument commemorates the fight for freedom and independence of the country. The square is a meeting and recreation place for locals and visitors, who can enjoy its architectural beauty and rich history. In its surroundings there are numerous restaurants, cafes and shops, making it a lively and busy place.

The Panama History Museum is a historical museum located on the ground floor of the Municipal Palace of Panama, in the Old Town of Panama City. This was inaugurated on December 14, 1977 by Dr. Reina Torres de Araúz, first on the second floor of the building. It is currently administered by the Ministry of Culture of Panama. This museum is framed in the context of Panamanian history, covering the Colonial Era (1501 to 1821), the Union of Colombia (1821 to 1903) and the Republican Era (1903 to the present).

The Church of San José is a Catholic temple located in the Old Town of Panama City. It was originally located in what is now Panama Viejo, the first place where Panama City was located. This building was saved from the fire that the city suffered in 1671, so part of the old convent was moved to the new city of Panama. This church houses one of the most important colonial treasures in the country, its Main Altar covered in gold leaf that dates back to the 18th century.

The Plaza is named after prominent Panamanian general Tomás Herrera, an important figure in the fight for Panama's independence from Spain. General Herrera organized a battalion of more than 1,500 soldiers and fought in Ayacucho and Junín. He was governor of Panama when the country was part of Colombia. Tomás Herrera was also one of the first, if not the first, to create the movement to separate Panama from Colombia. He died in Bogotá, murdered by a sniper in 1854.

Santa Ana Park was part of the suburb of the old city of Panama. At one time it was a square in front of the church that bears the same name. Before the Republican era it was used as a market and was the place where the people gathered to celebrate festivals. In 1890 – 131 years ago – the park was built and during the first 50 years of our republic it became the center of struggles for our sovereignty. In 1984 it was declared a national historical monument by Law 18.

The Church of Our Lady of Mercy is a Catholic temple located in the Old Town of Panama City. Initially it was located in the first location of the city, today called Panama Viejo. After the pirate attack and subsequent destruction of the city, the stone façade of this temple was moved piece by piece to the new city around the year 1680. In its atrium there are two chapels: One of the Virgin of Mercy and the another is a mausoleum. Likewise, this church is the guardian of an image of the Virgin of Charity of Cobre, venerated by Cubans.

The Mola Museum – MUMO is a space designed to expose the value of the mola in the Guna indigenous culture and Panama. On a tour of its 5 rooms, visitors will be able to learn about their evolution, how they are made, the meaning behind their designs and, above all, contemplate their art.

This tree-lined square was originally called San Francisco after the church that presides over it. It was not contemplated in the initial planning of the new Panama location. But a ravenous fire in 1756 destroyed 50 houses in the area, which produced a large vacant space on which nothing was built again. The square was renamed as a tribute to Simón Bolívar in 1926, the centenary of the Amphictyonic Congress. The bronze and granite sculptural group honors the Liberator and is the work of the Spanish Mariano Benlliure. It was commissioned by the Panamanian government, after the agreement reached between the Latin American countries. The Panamanian engineer Julio Poyló directed its erection.

This site corresponds to the tip of the city's peninsula, which was known as Punta de Chiriquí. Originally, it was a rammed earth parade ground for military uses; Later, it was also used as a prison. It maintained these functions until the beginning of the 20th century. Belisario Porras changed its name to Plaza de Francia, in remembrance of the failed French attempt to build the canal. In its surroundings are currently the National Institute of Culture, the French embassy, ​​the Esteban Huertas promenade, the monument to the sailors of the interoceanic canal and the Vaults. A statue of Pablo Arosemena, the fifth president of the Republic of Panama (1910-1912), is also erected in the square.