The Mosque of Amr ibn al-As, also called the Mosque of Amr, was originally built in 641–642 AD, as the center of the newly founded capital of Egypt, Fustat. The original structure was the first mosque ever built in Egypt and the whole of Africa.

Saint Virgin Mary's Coptic Orthodox Church, also known as The Hanging Church is one of the oldest churches in Egypt and the history of a church on this site dates to the third century. It belongs to the Coptic Orthodox Church of Alexandria.

a Greek Orthodox church within the Babylon Fortress in Coptic Cairo.It is part of the Holy Patriarchal Monastery of St George under the Greek Orthodox Patriarchate of Alexandria and all Africa.The church dates back to the 10th century (or earlier). The current structure was rebuilt following a 1904 fire,[construction was finished in 1909.Since 2009, the monastery's hegumen has had the rank of bishop with title Bishop Babylonos ("Bishop of Babylon").